What is Combined Hepatocellular Cholangiocarcinoma?
Combined hepatocellular cholangiocarcinoma is a rare type of cancer that affects both the liver and the biliary tract of the body and mainly originated from the liver cells of the body. It is a distinct type of cancer, and its diagnosis, treatment, and prognosis (the likely course of the disease) are uncertain.What is the Biliary Tree or Biliary Tract?
The biliary tree or system consists of the liver, gall bladder, and bile ducts. This system makes, store and secrete bile juice. Bile juice breaks down the fats into fatty acids thus helping in the digestion of the fats.Disease Causes
There is no well-known cause, but there are certain risk factors, such as past or current viral hepatitis infection, chronic inflammation of the gall bladder, liver fluke infestation (a parasitic infestation of the liver), excessive alcohol consumption, obesity, excessive or unnecessary use of steroids, iron supplements, and diabetes mellitus.Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are- Repeated pain in the abdomen
- Yellowish discolouration of the skin and the eyes (Jaundice)
- Constant body itching
- Nausea
- Vomiting
- Fever
- Pain in the upper right corner of the abdomen
- Unexplained weight loss
- Loss of appetite
Diagnosis
The following diagnostic techniques and procedures can be used to make a diagnosis. These are- Complete blood count (CBC)
- Blood coagulation profile
- BUN ( blood urea and nitrogen)
- Serum creatinine
- Liver function tests LFTs
- Amylase and lipase values
- Imaging techniques like CT scan, MRI, PET scan, X-Ray, and USG to detect the site and size of the tumour.
- Cholangioscopy (USG of the gall bladder and biliary tree)
- ·Cholangiography
- MRCP (Magnetic resonance cholangiopancreatography
- Serum bilirubin total, serum bilirubin conjugated and unconjugated
- Preoperative biopsy
Treatment
Surgical removal of the tumour is the most common and effective treatment option. Chemotherapy and radiation therapy are the treatment options in the advanced metastasis cases of the combined hepatocellular cholangiocarcinoma. Liver transplantation is the treatment option in cases of cirrhosis of the liver due to combined hepatocellular cholangiocarcinoma.What Support can we Give for Yolk Sac Tumour (Spinal Cord)?
Yolk Sac Tumour (Spinal Cord) is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Yolk Sac Tumour (Spinal Cord), we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:Donations — Without a Ribbon is grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.
