What is Chordoid Glioma of the Third Ventricle?
Chordoid Glioma of the Third Ventricle is a rare, low-grade brain tumour that grows slowly and develops in the anterior wall or roof of the third ventricle. It is believed to originate from the abnormal growth of ependymal cells.
Causes
The tumour arises due to the abnormal proliferation of ependymal cells, which are specialised glial cells in the central nervous system (CNS). These cells line the ventricles of the brain and the central canal of the spinal cord, playing a critical role in maintaining CNS function.
Signs and Symptoms
Patients with this condition may experience:
- Persistent headaches
- Nausea and vomiting
- Visual disturbances
- Memory problems
- Fainting episodes
- Increased heart rate
- Constant fatigue
Diagnosis
Gadolinium-enhanced MRI: Reveals a well-defined mass in the third ventricle with uniform enhancement.
Imaging Tests: CT scans and MRIs help determine the tumour’s location, size, and blood supply.
Treatment
- Surgical Removal: The primary treatment is complete surgical resection of the tumour. While complete removal often yields positive outcomes, the tumour’s deep location presents surgical challenges.
- Radiation Therapy: Used when complete resection is not possible to minimise the risk of recurrence and protect critical brain functions.
- Targeted Therapies: Ongoing research is exploring innovative treatments to improve outcomes.
Chordoid Glioma of the Third Ventricle remains a rare and complex condition, requiring careful diagnosis and treatment to manage its symptoms and reduce the risk of recurrence
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