CIC-Rearranged Sarcoma is a very rare and aggressive type of soft tissue cancer. It develops because of a specific genetic change involving a gene called CIC. In this condition, the CIC gene becomes abnormally joined with another gene, creating what is called a “gene...
SMARCB1-Deficient Sinonasal Carcinoma is a very rare and aggressive type of cancer that develops in the nasal cavity or the sinus areas around the nose. The term “SMARCB1-deficient” means that the tumour cells have lost a specific gene called SMARCB1, which normally...
Intraductal Tubulopapillary Neoplasm, often called ITPN, is a rare type of tumour that develops inside the ducts of the pancreas. The pancreas is an organ located behind the stomach that helps in digestion and blood sugar control. Inside the pancreas are small tubes...
NTRK Fusion–Positive Solid Tumours are rare cancers that arise from a specific genetic change called an NTRK gene fusion. Genes normally control how cells grow and divide. In this condition, part of the NTRK gene becomes abnormally attached to another gene. This...
Secretory Carcinoma is a rare type of cancer that most commonly develops in the breast or salivary glands, but it can occasionally occur in other parts of the body. It is defined by a specific genetic change called the ETV6–NTRK3 gene fusion. This fusion happens when...