What is Tubular Androblastoma or Sertoli Cell Tumor of the Ovary?Ovarian tubular androblastoma is a rare type of tumor that develops in the tissues that support the ovaries and accounts for only 0.1% of all ovarian tumors. These tumors usually develop in women between the ages of 7 and 79.It is a benign tumor that usually secretes the hormone estrogen and, less commonly, androgen. The tumor usually develops in one ovary and is mainly confined to the ovary.
What are Ovaries?The ovaries are an important part of the human reproductive system. The ovaries are small glands located on either side of the uterus through a tubular structure called the fallopian tubes. The ovaries produce eggs and hormones in females. These eggs are used for producing offsprings.
Disease CausesThere is no well-known cause; However, Certain hereditary and genetic mutations (faulty alterations in the genes) are believed to be responsible for the development of ovarian tubular androblastoma.
Signs and Symptoms
- A palpable (felt able) solid, painless mass in the pelvic region or lower part of the abdomen
- In Androgen secreting ovarian tubular androblastoma, patient can develop masculine features such as development of muscles, development of excessive hair on the body, enlargement of the clitoris and hoarse voice, acne on face,
- Patient can also suffer from heavy menstrual bleeding or irregular menstrual bleeding.
DiagnosisFollowing diagnostic tests and procedures can be used to make the diagnosis. These are
- Complete blood count ( CBC)
- Serum tumor markers
- Imaging techniques like ultrasonography (USG), CT-scan, MRI, and X-Ray to detect the site, size, and extent of the tumor.
- Pelvic examination through per- speculum examination of the vagina, cervix, and ovaries. A speculum is a gynecological instrument used to visualize the vaginal wall, cervix, uterus, and ovaries to detect any abnormality.