What is True Histiocytic Sarcoma?It is a type of malignant neoplasm (cancer) caused by the rapid, uncontrolled division of mature histiocyte cells. The tumour can form in the skin, lymph nodes, lungs, brain, and spinal cord.
What is a Histiocyte?A histiocyte is a type of white blood cell and part of the immune system of the body. They protect the body from disease-causing microorganisms thus play role in the defence system of the body.
Disease CausesThere is no well-known cause.
Disease EpidemiologyIt is a rare disease, with an incidence rate of 0.17% per 1,000,000 people. It usually affects older people with an average age of 61. It is slightly more common in males than females.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- Swelling or lumps on the skin
- Swelled or Enlarged lymph nodes
- Enlarged liver and spleen
- Weight loss
DiagnosisThe following diagnostic techniques and procedures can be used to make a diagnosis these are
- Complete blood count (CBC)
- LFT’s (Liver function test)
- Renal function tests
- Diagnostic imaging techniques such as USG, CT-scan, MRI, and PET scan can be used to detect the site, size, and extent of the tumour.
- Lumbar puncture Test
- Tumour biopsy and histopathology