What is T-cell Prolymphocytic Leukemia?
This is a rare and aggressive type of cancer that results from the rapid, uncontrolled division of mature T cells, also called T lymphocytes. T cells, or T lymphocytes, are the main components of the body’s immune system that helps to fight infections. T-cell prolymphocytic leukemia usually affects the blood, bone marrow, liver, spleen, lymph nodes, and skin.
Disease Epidemiology
It is rare cancer that is slightly more prevalent in men than in women. It usually affects people over the age of 30, with an average age of 61.
Disease Causes
It develops due to uncontrolled division of mature T cells due to hereditary or specific genetic mutation (faulty alteration in the gene).
Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are
- Enlarged or swelled lymph nodes
- Enlargement of the spleen
- Enlargement of the liver
- Lesions and rash on the skin
- Fever
- Excessive sweating at the night
- Unintentional Weight loss
- Anemia ( paleness of the palms and eyes, Difficulty In breathing while doing any physical activity, Constant Fatigue, memory weakness).
- Symptoms of thrombocytopenia (decreased platelet count): easily bleeding and bruising on minor injury, small red or purple spots under the skin, bleeding from nose or gums, unusually heavy menstrual bleeding, recurrent headache.
Diagnosis
The following are the diagnostic tests that help to diagnose T cell pro-lymphocytic Leukemia.
- Complete blood count (CBC) with peripheral smear
- Blood coagulation profile
- Bone marrow aspiration and cytology
- Immunohistochemistry
- EBV antibodies test
- CT- scan, MRI, PET scan, Ultrasonography (USG), and X-Ray to detect the site and extent of care.
Treatment
Chemotherapy, radiation therapy, and stem cell transplantation are the main treatment options.
What support can we give for T-cell Prolymphocytic Leukemia?
T-cell Prolymphocytic Leukemia is a rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. We provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from a rare cancer such as T-cell Prolymphocytic Leukemia, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways: Donations — Without a Ribbon is grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences. Sponsorship — If you wish to sponsor our charity, please contact us using this form. Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.
