What is Spermatocytic Seminoma with Sarcoma of the Testes?Spermatocytic seminoma with sarcoma is a very uncommon form of testicular germ cell cancer that manifests as sarcomatous alterations (i.e. involves bone, cartilage, and other soft tissues and becomes more cancerous and lethal) in the tumour in 5-6% of cases. The term “germ cell tumour” refers to tumours that develop from the testes or ovaries, respectively, in males and females, which produce germ cells. Often, it affects men in their fifth decade of life.
Disease CausesThere is no known cause, but it is thought that certain genetic and hereditary mutations, as well as exposure to certain environmental factors, can cause immature spermatogonia (an early stage in the formation of sperm) to multiply or divide uncontrollably, which can result in the development of spermatocytic seminoma with sarcoma of the testicles.
Signs and Symptoms
- Painless enlargement of the testes
- Swelling of the testes
- Palpable (felt able, touchable mass in the testes) in the scrotum)
- Feeling of heaviness in the testes
- Enlargement of breasts in males
- Pain in the back or groin region
- Change in the size or shape of the testes
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are
- A physical examination of the pelvic area (hip) to see unusual changes in the scrotum, to asses any mass or lump in this area
- Imaging tests like scrotal ultrasonography (USG), CT-scan testis, CT-scan abdomen, CT scan chest, and brain to detect the tumour size, site and metastasis.
- Tumour Biopsy