What is Sarcomatoid Mesothelioma of Lung?Sarcomatoid mesothelioma of the lung is a rare type of lung cancer that originates from sarcomatoid cells of mesothelium layer. It is caused by exposure to asbestos over a long period of time. It accounts for 10-20%of all lung cancers. Sarcomatoid mesothelioma of the lung is usually formed in the form of separate nodes and lesions. These nodes and lesions tend to spread to surrounding and other distant parts of the body. It is usually diagnosed with great difficulty since the cells of sarcomatoid mesothelioma of the lung in the initial stages of the disease look like normal cells. Sarcomatoid mesothelioma of the lung usually develops within 10-50 years. It shows poor prognosis (probable course of the disease). Survival is less than 6 months after the diagnosis of the disease.
What is mesothelioma of lung?Mesothelioma of the lung is a type of lung cancer that arises from a thin layer of tissues that forms the outer lining or layer of most of the body’s internal organs. This layer of tissues is called mesothelium layer. In case of the lungs and chest cavity, this mesothelial layer is called the pleura, or pleural membrane, which covers the lungs and chest cavity.
Disease CausesSarcomatoid mesothelioma of the lung is caused by exposure to a substance called asbestos. When a person inhales asbestos fibres over a long period of time, it can accumulate in the lining of the lungs and cause mesothelioma lung cancer. Exposure to certain radiations or prior radiation therapy is also a risk factor for the development of sarcomatoid mesothelioma of the lung.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- Persistent dry cough
- Shortness of breath or difficulty in breathing
- Pleural effusion (it is a condition in which excessive fluid accumulates between the lung and its outer membranes)
- Pain in the chest
- Clubbing of nails
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are;
- Imaging techniques like Chest X-ray, CT-scan, MRI, and PET scan to see the site, size, and extent of the tumour.
- Tumour biopsy ( lung tumour biopsy to remove a small sample of lung tissue for histopathological examination)
- Sputum cytology
- USG-guided fine needle aspiration cytology