What is the Renal Cell Carcinoma of Collecting Duct?
Renal Cell Carcinoma of Collecting Duct of the kidney is a rare type of kidney cancer; it originates from the principal cells of the collecting duct. The collecting duct is the last part of the long convoluted tubule that collects urine from the nephron and delivers it to the urinary bladder through ureters.
The basic structure of the kidney is composed of many nephrons and tiny tubules. The nephron is the main structural and functional unit of the kidneys, the function of the nephron is to filter the blood, reabsorb the essential substance and remove waste and harmful substances in the form of urine.
Disease Epidemiology
It is a rare cancer account for 1-3% of all kidney cancer.
Disease Etiology
There is no well-known cause, however, certain genetic mutations are considered responsible for the development of Renal Cell Carcinoma of Collecting Duct.
Signs and Symptoms
In most cases, there are no symptoms, and cancer or collecting duct tumour is detected on the occasional radiologic examination. In advance cases, the patient may develop the following signs and symptoms. These are
- Pain in the loin
- Passage of blood or blood particles in the urine
- A palpable mass in the loin or abdomen
- Unexplained weight loss
- Night sweats
- High blood pressure
- Fever
- Lethargy
Diagnosis
The following diagnostic tests and procedures can be used to make a diagnosis. These are
- Imaging techniques like CT-abdomen and pelvis, USG abdomen and pelvis, MRI, CT-chest, and X-ray to assess the site, size, extent, and distant metastasis of the tumour.
- Renal arteriography ( Ultrasonography of the main artery of the kidney)
- Venography
- CT-scan and MRI brain to detect the distant metastasis of the tumour
Treatment
Surgical removal of the tumour, radiation therapy, chemotherapy, thermal ablation, and immunotherapy are the main treatment options.
What Support can we Give for Medullary Thyroid Carcinoma?
Medullary Thyroid Carcinoma is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Medullary Thyroid Carcinoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
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