What is Prolymphocytic Leukemia?
Prolymphocytic leukemia is a type of white blood cell cancer that occurs as a result of uncontrolled division or multiplication of immature white blood cells. It can originate from premature T-lymphocytes or B-lymphocytes. Premature T and B lymphocytes go through different stages of development and become mature cells. The disease can affect the liver, spleen, bone marrow, lymph nodes, and skin.What are B-lymphocytes?
B-lymphocytes are a type of white blood cell that is part of the body’s immune system and helps fight off harmful bacteria, viruses, algae, and fungi.What are T lymphocytes?
T cells or T-lymphocytes are the type of white blood cells that help to fight various pathogens (Disease-causing microorganisms or agents).Disease Causes
There is no well-known cause, however, certain hereditary and genetic mutations (faulty alterations in the genes) are considered responsible for the development of prolymphocytic leukemia.Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are- Increase calcium level in the blood
- Swelling and enlargement of the lymph nodes of the neck, armpits, and groin
- Constant feeling of tiredness
- Rashes or lesions on the skin
- Unexplained weight loss
- Constant Fever
- Excessive sweating at night
- Cough
- Enlargement of the lymph nodes
- Enlargement of the spleen
- Pain in the bones
- Pain in the joints
Diagnosis
The following diagnostic tests and procedures can be used to make a diagnosis. These are- Urine complete examination (UCE) to detect any urinary tract infection and blood in the urine
- Complete blood count (CBC)
- Liver function tests (LFT’s)
- Imaging techniques like CT scan, USG, MRI, CT-chest, and X-ray to assess the site, size, extent, and distant metastasis of the tumour.
- Tumour biopsy and histopathological examination
- Bone marrow biopsy
- Immunohistochemistry
Treatment
Chemotherapy, radiation therapy, immunotherapy, targeted therapy, and stem cell transplantation are the main treatment option.What Support can we Give for Prolymphocytic Leukemia?
Prolymphocytic Leukemia is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Prolymphocytic Leukemia, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:Donations — Without a Ribbon is grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.
