What is Primary Pulmonary Colloid Adenocarcinoma Lung?Primary pulmonary colloid adenocarcinoma of the lung is a rare type of lung cancer that can produce mucous (phlegm), as its name suggests. It shows a poor prognosis (likely course of the disease). If we see the tumour cells of the primary colloid adenocarcinoma of the lung under a microscope for histopathological examination of the tumor, we can observe copious amounts of mucus in the tumour cells. Primary pulmonary colloid adenocarcinoma is a very rare type of cancer and accounts for approximately 0.24% of all lung cancers. The size of the primary pulmonary colloid adenocarcinoma varies from 1.8cm to 6.5cm. The median 5-year survival rate for patients with primary colloid lung adenocarcinoma is 51%.
Disease Etiology (Causes)There is no definite well-known cause. However, certain genetic mutations (alteration or deletion in normal genes or chromosomes) and long-term cigarette smoking are potential risk factors for the development of primary pulmonary colloid adenocarcinoma.
Signs and SymptomsSigns and symptoms depend on the extent and spread of the disease to other organs or parts of the body. If the cancer is limited to the lungs, the patient will only experience signs and symptoms of the respiratory system. At the same time, in cases where this cancer spreads to other parts of the body, the patient also experiences B symptoms of cancer
The common respiratory symptoms are
- Persistent cough
- Cough with sputum
- Feeling of tightness in the chest
- Chest pain
- In the advanced stage of the disease, there may be difficulty in breathing
- The other less common symptoms are sore throat, pain in the abdomen, and diarrhea
- Excessive sweating at night
- Weight loss
- Bone pains
Diagnosis and TreatmentThe following diagnostic tests and procedures can be used to make a diagnosis. These are;
- Imaging techniques like Chest X-ray, CT-scan, MRI, and PET scan to see the site, size, and extent of the tumour.
- Tumour biopsy ( lung tumour biopsy to remove a small sample of lung tissue for histopathological examination)
- Sputum cytology
- USG-guided fine needle aspiration cytology