What is Primary Cutaneous Diffuse Large B Cell Lymphoma Leg Type?
Primary cutaneous diffuse large B cell lymphoma of the leg is aggressive cancer that arises from B lymphocytes and usually forms lesions on the skin of the legs. It is aggressive cancer and has a poor prognosis (probable course of the disease).What is a B Lymphocyte?
B-lymphocyte is a type of white blood cell that forms antibodies to fight against foreign agents and pathogens and plays a role in the body’s defense system.Disease Etiology (Causes)
There is no well-known cause.Disease Epidemiology
It accounts for approximately 5-10% of all diffuse large B-cell lymphomas. It usually affects the elderly, with the peak incidence in the 7th decade of life.Signs and Symptoms
- Reddish-brown nodules on the lower part of the leg, usually below the leg
- Tumor nodules can also appear on the skin of the chest, head, neck, and upper part of the arms
Diagnosis
The following diagnostic techniques and procedures can be used to make a diagnosis these are- Diagnostic imaging techniques such as USG, CT-scan, MRI, and PET scan can be used to detect the site, size, and extent of the tumor.
- Tumor biopsy
- Histo-pathological examination
- Cytogenetics