What is Melanoma Of The Penis?Penile melanoma is a very rare cancer, accounting for approximately 0.1% of all melanoma cases. Melanoma is a cancerous skin cancer that develops from skin cells that produce pigment. Penile melanoma is a cancer of the penis that forms from the pigment-producing cells in the skin of the penis. It is a very rare cancer as only 220 cases of penile melanoma have been reported worldwide so far. The most common site of the cancer is the glans penis (rounded head or tip) part of the penis.
Disease EpidemiologyIt accounts for 0.7% of penile cancers and 0.1% of melanoma cancers. The average age for the development of the disease is 44 years.
Disease Etiology (Causes)There is no known cause. However, a history of sexually transmitted diseases, trauma, and certain medications are risk factors for developing penile lymphoma.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- Masses or lumps in the shaft of the penis
- Frequent urge to pass urine
- Difficulty in passing urine
- Pain while passing urine
- Ulcer on the penis
- Abnormal discharge from the penis
- Swelling and enlargement of the pelvic lymph nodes
- Pain in the abdomen
- Night sweats
- Weight loss
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are
- Imaging tests, such as computed tomography CT-scan, MRI, and PET scans, to examine the location, size, and extent of the tumor.
- Complete blood count (CBC)
- Liver function test (LFT’s)
- Renal functional test (RFT’s)
- Urine complete examination to rule out certain infections which may be the cause of penile lymphoma
- Immunohistochemistry tests
- Biopsy of the cancerous mass or lump and its histopathological examination