What is Parosteal Osteosarcoma?Partial osteosarcoma is a slowly growing subtype of bone-forming cancer that arises from the outer layer of the periosteum. The periosteum is a thin layer that covers the outer surface of the bone and provides structural integrity and produces bone-forming cells. In only 15% of cases, it can spread to the distant parts of the body (metastasis). It can invade the bone from which it arises. The bones of the legs and arms are common sites for the development of parosteal osteosarcoma.
Disease EpidemiologyIt accounts for approximately 5% of all bone-forming cancers. It is more common in adolescents and young adults with an average age of 30 years for developing parosteal sarcoma. It is more common in women than in men.
Disease Etiology (Causes)There are no well-known causes, however, certain genetic mutations and exposure to certain radiation and chemicals are considered risk factors for developing parosteal osteosarcoma. Signs and symptoms The patient may suffer from the following signs and symptoms. These are
- The painless slowly growing mass which is firm and immobile
- The most common sites for parosteal osteosarcoma are the thighs, a mass behind the knee, a mass near the elbow, a mass near the wrist, or a mass near the ankle in the lower leg.
DiagnosisThe following diagnostic techniques and procedures can be used to make a diagnosis. These are
- Imaging diagnostic techniques such as X-Ray, CT-scan, and PET-scan can be used to detect the site, size, and extent of the tumor.
- Tumor Biopsy