What is Paraosteal Osteogenic Carcinoma of the Bone?Paraosteal osteogenic carcinoma is a rare type of low-grade cancer that usually forms on the surface of bones. It especially develops on the surfaces of the bones of the forearm, i.e., the radius and ulna, as well as the bones of the lower leg, i.e., the tibia and fibula. It grows slowly and has a low tendency to spread to the other parts of the body. It usually affects people between the ages of 15-30 years.
Disease CausesThere is no well-known cause however certain hereditary and genetic mutations are considered responsible for the development of paraosteal osteogenic carcinoma of the bone.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- Pain in the affected bone particularly with exertion or doing any physical activity
- Limp (Difficulty in walking or writing due to damage or fracture in bone of arm or leg)
- Broken bones
- Night sweats
- Weight loss
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are
- Complete blood count (CBC)
- Lactic dehydrogenase (LDH)
- Alkaline Phosphatase (ALP)
- Liver Function Tests (LFTs)
- Renal Function Tests (RFTs)
- Imaging diagnostic techniques such as X-Ray, CT-scan, and PET-scan can be used to detect the site, size, and extent of the tumour.
- Tumour Biopsy