What is Neurofibroma of the Mediastinum?Mediastinal neurofibromas are benign (non-cancerous) tumours of the peripheral nerves located in the mediastinum. It is commonly developed in people who have a medical condition called neurofibromatosis. Neurofibromatosis is a genetic condition in which tumours form from nerve tissues. Neurofibroma of the mediastinum is more common in young adults and children. These tumours can also develop in the head and neck region, particularly in children.
What is Mediastinum?The mediastinum is a space in the thorax that contains the heart, thymus gland, portions of the esophagus trachea, and other structures.
Disease CausesThere is no well-known cause, however, certain hereditary and genetic mutations are considered responsible for the development of neurofibroma of the mediastinum.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- Difficulty in breathing
- Pain in the chest
- Unexplained weight loss
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are;
- Imaging techniques like Chest X-ray, CT-scan, MRI, and PET scan to see the site, size, and extent of the tumor.
- Tumour biopsy (tumour biopsy to remove a small sample of tissue for histopathological examination)
- Sputum cytology
- USG-guided fine needle aspiration cytology