What is mixed cellularity Hodgkin’s lymphoma?Mixed cellularity Hodgkin’s Lymphoma is a subtype of Hodgkin’s lymphoma (white blood cell cancer). It is among the most common types of Hodgkin’s lymphoma. The most common sites for Hodgkin’s lymphoma are the lymph nodes in the neck, armpits, and abdomen. Other less frequent sites are the liver, spleen, and bone marrow.
Disease causesThere is no well-known cause, but there is a link between current or previous Epstein virus infection and the development of mixed-cell Hodgkin’s lymphoma.
Disease EpidemiologyMixed Cellularity Hodgkin’s lymphoma is the second most common type of Hodgkin’s lymphoma. A person with an Epstein-bar virus or HIV (AIDS) infection is more vulnerable to developing mixed-cell Hodgkin lymphoma due to the body’s weak immune system. It is more common in older adults between the age of 55-74 and children under the age of 14. It is equally common in both males and females.
Signs and symptomsThe patient may suffer from the following signs and symptoms. These are
- Enlarged or swollen lymph nodes ( appearance of hard masses) of the neck armpit or abdomen
DiagnosisThe following are the diagnostic tests that help diagnose the nodular lymphocyte Predominant Hodgkin lymphoma.
- Complete blood count (CBC) with peripheral smear
- Blood coagulation profile
- Bone marrow aspiration and cytology
- EBV antibodies test
- CT- scan, MRI, PET scan, Ultrasonography (USG), and X-Ray to detect the site and extent of care.