What is Medullary Adenocarcinoma of the Colon?
Medullary adenocarcinoma of the colon is a rare and distinct type of colorectal cancer. It is characterized by a specific growth pattern and cellular appearance, with cells that are poorly differentiated yet have a lower rate of metastasis compared to other types of colon adenocarcinomas. This type of cancer is more commonly observed in elderly patients and often has a genetic component, being associated with microsatellite instability and Lynch syndrome.Symptoms
Symptoms of medullary adenocarcinoma of the colon can be similar to other colorectal cancers and may include:- Changes in bowel habits, such as diarrhea, constipation, or a change in stool consistency.
- Presence of blood in the stool or rectal bleeding.
- Abdominal pain or discomfort.
- Unexplained weight loss.
- Fatigue and weakness.
- In some cases, there may be no symptoms, and the cancer is detected during routine screening.
Disease Aetiology (Causes)
The exact cause of medullary adenocarcinoma of the colon is not fully understood. However, its association with microsatellite instability suggests a genetic component. It is often linked with Lynch syndrome, a hereditary condition that increases the risk of colon and other types of cancer.Diagnosis
Diagnosing medullary adenocarcinoma of the colon typically involves:- Colonoscopy: To visually inspect the colon and obtain a biopsy of any suspicious areas.
- Imaging Studies: Such as CT scans, MRI, or PET scans, to assess the extent of the disease.
- Biopsy: A tissue sample is examined under a microscope for a definitive diagnosis.
- Genetic Testing: To check for microsatellite instability and potential hereditary conditions like Lynch syndrome.
Treatment
Treatment for medullary adenocarcinoma of the colon may include:- Surgery: The primary treatment, typically involves the removal of the affected portion of the colon and adjacent lymph nodes.
- Chemotherapy: Used post-surgery, especially if there are risk factors for recurrence or metastasis.
- Targeted Therapy and Immunotherapy: There may be options depending on the genetic characteristics of the tumour.
- Radiation Therapy: Less commonly used for this type of colon cancer but may be considered in specific circumstances.
What support can we give for Medullary Adenocarcinoma of the Colon?
Medullary Adenocarcinoma of the Colon is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Medullary Adenocarcinoma of the Colon, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:Donations — Without a Ribbon are grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
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