What is Malignant Mixed Mullerian Tumour of the Uterus?
A malignant mixed Mullerian tumour of the uterus, also known as carcinosarcoma, is a rare type of cancer that contains both carcinoma (cancer of the epithelium) and sarcoma (cancer of the connective tissue) components. This aggressive tumour represents only a small fraction of all uterine cancers but is responsible for a significant number of deaths due to its tendency to spread early and recur after treatment.
Disease Aetiology (Causes)
Malignant mixed Mullerian tumour of the Uterus represents about 3-5% of all uterine cancers. The exact cause of the malignant mixed Mullerian tumour of the uterus is unknown, but it is likely to involve genetic mutations that lead to uncontrolled cell growth and division. Risk factors that may increase the likelihood of developing a malignant mixed Mullerian tumour of the uterus include obesity, use of tamoxifen (a drug used in the treatment of breast cancer), and a history of pelvic radiation therapy.
Diagnosis
The diagnosis of malignant mixed Mullerian tumour of the uterus often involves:
- Detailed medical history and physical examination
- Endometrial biopsy or dilation and curettage (D&C) to obtain tissue for examination under a microscope
- Imaging tests such as ultrasound, CT scan, or MRI to ascertain the size, location, and extent of the tumour
Treatment
The treatment for malignant mixed Mullerian tumour of the uterus typically involves a combination of strategies:
- Surgery: The primary treatment, involves the surgical removal of the uterus (hysterectomy), along with the fallopian tubes and ovaries.
- Radiation Therapy: This can be used before surgery to shrink the tumour, or after surgery to kill any remaining cancer cells.
- Chemotherapy: This is often used in combination with surgery and radiation therapy, particularly in more advanced cases or if the cancer recurs.
Other Names
Malignant Mixed Mullerian Tumour of the Uterus can also be referred to by the following terms:
- Uterine Carcinosarcoma
- Metaplastic Carcinoma of the Uterus
- MMMT of the Uterus
- Carcinosarcoma of the Uterus
What Support can we Give for Malignant Mixed Mullerian Tumour of the Uterus?
Malignant Mixed Mullerian Tumour of the Uterus is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Malignant Mixed Mullerian Tumour of the Uterus, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
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