What is lymphoepithelioma like carcinoma of the urinary bladder?
Lymphoepithelioma-like carcinoma of the urinary bladder is a rare subtype of transitional cell carcinoma or urothelial carcinoma. It is characterized by the uncontrolled multiplication of certain types of white blood cells in the area of the tumour, which can be observed during histopathological examination under a microscope, taking the tumour tissue. It usually develops in the bladder, but it can also develop in the urethra and urinary tract. The urethra is a tube that connects the bladder to the outer opening of the urethra to drain urine from the body.
It is rare cancer, accounting for 0.4% to 1.3% of all urinary bladder cancers. In males, it is slightly common than in females. It usually affects older people over 65 years of age.
Disease Etiology (Causes)
There is no well-known cause, however, certain genetic mutations (faulty alterations in certain genes) are considered responsible for the development of the disease.
Signs and symptoms
The patient may suffer from the following signs and symptoms. These are
- (Hematuria) Presence of blood in urine without any pain
- Usually diagnosed in advanced stages
The following diagnostic tests and procedures can be used to make a diagnosis. These are
- Urine complete examination (UCE) to detect any urinary tract infection and blood in the urine
- Complete blood count (CBC)
- Renal Function Test (RFT’s) to check the serum urea and creatinine
- Liver function tests (LFT’s)
- Imaging techniques like CT abdomen and pelvis, USG abdomen and pelvis, MRI, CT-chest, and X-ray to assess the site, size, extent, and distant metastasis of the tumor.
- Cystoscopy; is similar to an ultrasound examination of the urinary bladder, which allows direct visualization of the ureter with cystoscopy.
- Urinary cytology; is a microscopic examination of the cells present in urine and their characteristics.
- Tumour biopsy and histopathological examination
Surgical resection (cutting off the tumor or diseased part and rejoining the reaming healthy part of the organ or tissue to keep it functional) of the tumor along with the radiation therapy and chemotherapy are the main treatment options along with surgery.
What Support can we Give for Lymphoepithlioma like carcinoma of the Urinary Bladder?
Lymphoepithlioma like carcinoma of the Urinary Bladder is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Lymphoepithlioma like carcinoma of the Urinary Bladder we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
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