What is Liposarcoma?It is a rare type of cancer that originates from the fat cells or tissues of the body. The most common sites of its origination are the thighs and retroperitoneum (abdominal cavity/space behind the peritoneum) of the abdomen; however, it can develop in any part or site of the body.
Disease EpidemiologyWorldwide annual frequency of occurrence of new cases of liposarcoma is 2.5 cases per million populations. It is a more prevalent cancer type of soft tissue and bones making up to 17% of the soft tissue sarcoma and 3% liposarcoma of head and neck region (usually neck and cheek). The most common sites for the development of tumors are abdomen and legs. Liposarcoma is more common in males as compared to females. The mean age at the diagnosis of the tumor is 50 years in most of the reported cases. However, Liposarcoma is also prevalent in adolescents and young adults to some extent but is very rare in children.
Disease Etiology (Cause)There is no exact well-known cause is found. Certain genetic mutations are considered responsible for the development of the Tumor.
Signs and SymptomsMost liposarcoma patients have no symptoms until the tumor is large and puts pressure on adjacent structures, causing tenderness, pain, or functional disorders. The patient may have the following signs and symptoms. These are
General (Overall) Symptoms Associated with The Liposarcoma
- Ulceration of the tumor or injury of the adjacent regions.
- Swelling which is painful
- Weight loss
- Fatigue and lethargy
- Night sweats
- Numbness of the affected limb
- Enlargement and swelling of lower legs veins.
- Fatigue and Lethargy
Signs and Symptoms Associated with Liposarcoma of the Abdomen (Retroperitoneum)
- Palpable ( touchable) Abdominal mass/lump
- Abdominal Pain
- Nausea Vomiting
- Weight loss