What is Liposarcoma?
Liposarcoma is a rare type of cancer that originates from the fat cells or tissues of the body. The most common sites of its origination are the thighs and retroperitoneum (abdominal cavity/space behind the peritoneum) of the abdomen; however, it can develop in any part or site of the body.
Disease Epidemiology
Worldwide annual frequency of occurrence of new cases of liposarcoma is 2.5 cases per million populations. It is a more prevalent cancer type of soft tissue and bones making up to 17% of the soft tissue sarcoma and 3% liposarcoma of head and neck region (usually neck and cheek). The most common sites for the development of tumors are abdomen and legs. Liposarcoma is more common in males as compared to females. The mean age at the diagnosis of the tumor is 50 years in most of the reported cases. However, Liposarcoma is also prevalent in adolescents and young adults to some extent but is very rare in children.
Disease Etiology (Cause)
There is no exact well-known cause is found. Certain genetic mutations are considered responsible for the development of the Tumor.
Signs and Symptoms
Most liposarcoma patients have no symptoms until the tumor is large and puts pressure on adjacent structures, causing tenderness, pain, or functional disorders. The patient may have the following signs and symptoms. These are
General (Overall) Symptoms Associated with The Liposarcoma
- Ulceration of the tumor or injury of the adjacent regions.
- Pain
- Swelling which is painful
- Weight loss
- Fatigue and lethargy
- Fever
- Night sweats
Signs and Symptoms Liposarcoma of the Lower Limb (Leg)
- Numbness of the affected limb
- Enlargement and swelling of lower legs veins.
- Fatigue and Lethargy
Signs and Symptoms Associated with Liposarcoma of the Abdomen (Retroperitoneum)
- Palpable ( touchable) Abdominal mass/lump
- Abdominal Pain
- Nausea Vomiting
- Weight loss
Diagnosis and Treatment
Definite diagnostic tests to diagnose the liposarcoma tumors are tumor biopsy and histopathology, Fine needle aspiration cytology, and cytogenetic study of the specimen. Radiological techniques like CT scan, MRI, USG, and X-ray also recommended locating the size and site of the tumor.
Treatment
For the tumor which is not widespread, wide local surgical excision of the tumor is the most effective treatment option. Chemotherapy and radiotherapy are the treatment options for tumors that spread to the distant parts of the body and not confined to its site of origin.
What Support can we Give for Liposarcoma?
Liposarcoma is a rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Liposarcoma we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
