What is Haematodermic Neoplasm?A haematodermic neoplasm is an aggressive killer blast cell lymphoma (cancer of white blood cells) that manifests as a skin lesion, most often appearing on the scalp (skin of the head), trunk, and extremities (arms and legs). Natural killer cells are white blood cells that play a role in the body’s defence system by directly killing disease-causing viruses.
Disease EpidemiologyIt usually affects older adults. It is commonly limited to the skin but can affect the blood, bone marrow, lymph nodes, and other organs of the body.
Disease Etiology (Causes)There is no well-known cause, however, genetic mutations are considered responsible for the development of haematodermic neoplasm.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- Single or multiple skin lesions on the skin of head, trunk, or limbs (arms and legs)
- Red or dark-coloured skin lesions
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are
- Blood flow cytometric analysis
- Skin biopsy
- Bone marrow aspiration cytology