What is Germinoma Of The Brain?A germinoma is cancer that usually arises from the germ cells (eggs and sperm) of the male and female reproductive organs. These eggs and sperms usually move to the ovaries and testes during fetal life. But in some people, during fetal life, they cannot migrate to their proper organs and places and begin to multiply in the brain and spinal cord. These tumors or cancers are called brain germinomas.
Disease EpidemiologyIt is a rare brain cancer in children and adolescents. The five-year treatment survival rate is 85%. It is slightly more common in men than in women. The average age of development of cerebral germinoma ranges from 10 to 21 years. In 22% of cases, it can spread to other distant parts of the body.
Disease Etiology (Causes)The inability of gonadal cells (sperm and egg cells) to migrate to the right place, that is migration of eggs in ovaries and sperm in the testes during fetal life, is the main cause of cerebral germinoma.
Signs and SymptomsSigns and symptoms vary depending on the size and location of the tumor in the brain. The patient may suffer from the following signs and symptoms. These are
- Constant headache
- Changes in mood and behavior
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are
- Imaging tests such as X-Ray, CT-scan (computerized tomography), PET-scan (Positron emission tomography) help detect the site, size, and location of the tumor.
- Tumor biopsy and histopathological examination