What is Ganglioneuroma of the Mediastinum?
Mediastinal ganglioneuroma is a rare type of benign (non-cancerous) tumour originating from the peripheral nerve cells of the sympathetic nervous system. It mainly affects adolescents and young adults. Although mediastinal ganglioneuroma is a benign tumour, large tumours can compress underlying vital organs, which can cause complications.What is a Sympathetic Nervous System?
The sympathetic nervous system connects the brain with all the internal organs of the body with nerves extending from the spinal cord and innervating these organs. The sympathetic nervous system works in a fight-and-flight by increasing the heart rate, increasing blood flow to the muscles of the arms and legs, and decreasing blood flow to the skin.What is Mediastinum?
The mediastinum is a space in the thorax that contains the heart, thymus gland, portions of the esophagus trachea, and other structures.Disease Causes
There is no well-known cause; however, some hereditary and genetic mutations are thought to be responsible for the excessive division or multiplication of peripheral neuronal cells, which can lead to ganglioneuroma of the mediastinum.Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are- Pain in the back
- Pain in the chest
- Difficulty in breathing
- Persistent dry cough
- Persistent fatigue (tiredness)
- Fever
- In advanced stages, the enlargement of the lymph nodes can also occur
Diagnosis
The following diagnostic tests and procedures can be used to make a diagnosis. These are;- Imaging techniques like Chest X-ray, CT-scan, MRI, and PET scan to see the site, size, and extent of the tumour.
- Tumour biopsy (tumour biopsy to remove a small sample of tissue for histopathological examination)
- Sputum cytology
- USG guided fine needle aspiration cytology
Treatment
Surgical resection (surgical removal of the damaged part of the body) of the tumour is the main treatment; other treatment options are chemotherapy and radiation therapy.What Support can we Give for Ganglioneuroma Mediastinum?
Ganglioneuroma Mediastinum is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Ganglioneuroma Mediastinum, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:Donations — Without a Ribbon is grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.
