What are Familial Adenomatous Polyposis and Desmoids Disease?
Familial adenomatous polyposis is an inherited disorder characterized by the development of several benign abnormal tissue growths called adenomatous polyps, which originate from the glandular epithelial tissue of the large intestine, also called the colon. Although they are not cancerous, however, they can invade local and nearby tissues and cause death.
Disease Etiology (Causes)
A mutation in a particular gene is the cause of the development of familial adenomatous polyposis and desmoids disease.
Disease Epidemiology
It is a rare disease and makes approximately 1% of the large intestine and rectal cancer. It is slightly more predominant in females than males. It is more common in the younger population.
Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are
- Pain in the abdomen
- Nausea
- Vomiting
- Constipation
Diagnosis and Treatment
The following diagnostic tests and procedures can be used to make a diagnosis. These are
- Complete blood count (CBC)
- Blood coagulation profile
- BUN ( blood urea and nitrogen)
- Serum creatinine
- Liver function tests LFT’s
- Amylase and lipase values
- Imaging techniques like CT-scan, MRI, PET-scan, X-Ray, and USG to detect the site and size of the tumor.
- Colonoscopy
- Preoperative biopsy
Treatment
Total proctocolectomy (surgical removal of the colon) is the main treatment option. In malignant cases, total proctocolectomy with adjuvant chemotherapy is the main treatment option.
What Support can we Give for Desmoids Disease FAP?
Desmoids Disease FAP is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Desmoids Disease FAP we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
