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Endometrial Stromal Sarcoma of the Vagina – Symptoms, Treatment & Support

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Posted by Matthew O’Connor | Apr 24, 2023

What is Endometrial Stromal Sarcoma of the Vagina?

Endometrial stromal sarcoma of the vagina is an exceedingly rare form of cancer, representing a minute fraction of all vaginal cancers. These tumours originate from the stromal cells, which form the supportive framework of the vaginal tissues. Endometrial stromal sarcomas are usually slow-growing tumours, but they have the propensity to recur and metastasize, spreading to other parts of the body. The rarity of this condition has led to a limited understanding of its development, optimal treatment methods, and long-term prognosis.

Disease Etiology (Causes)

The exact cause of vaginal endometrial stromal sarcoma is still unknown. It is likely to arise due to DNA mutations in the stromal cells, causing them to grow and divide in an uncontrolled manner, forming a tumour. No specific risk factors have been identified for this condition, but general cancer risk factors such as family history of cancer, certain genetic mutations, and exposure to specific chemical agents could potentially contribute to its development.

Diagnosis

Endometrial stromal sarcoma is usually diagnosed through a series of steps that may include:

  • Detailed medical history and physical examination
  • Biopsy of suspicious tissues
  • Imaging tests, such as ultrasound, CT scan, or MRI, to determine the size and location of the tumour, and to assess if the cancer has spread to other parts of the body.

Treatment

The treatment for endometrial stromal sarcoma of the vagina often involves a combination of approaches, including: Surgery: The main treatment for this condition typically involves the removal of the tumour, and in more advanced cases, removal of the entire vagina or nearby structures might be necessary. Radiation Therapy: This can be used before surgery to shrink the tumour, or after surgery to kill any remaining cancer cells. Hormone Therapy: Since these tumours often respond to hormonal changes, hormone therapy can be used to slow the growth of the tumour. Chemotherapy: In certain cases, chemotherapy can be utilized either before or after surgery to manage the cancer.


What Support can we Give for Endometrial Stromal Sarcoma of the Vagina?

Endometrial Stromal Sarcoma of the Vagina is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as the Endometrial Stromal Sarcoma of the Vagina, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

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Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:

Donations — Without a Ribbon are grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.

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