What is Desmoid Disease or Tumour?A desmoid tumour is a benign tumour that develops from the connective tissues of the body. Connective tissues are tissues that bind, separate, or support other tissues or organs, thus forming the structure of organs and providing strength to organs and the body. They most often occur in the abdomen, shoulders, upper arms, and legs. Desmoid tumours are not malignant, but they can invade the local structure and can recur after complete removal by surgery. In majority cases the development of the single desmoid tumour is observed but cases with multiple desmoid tumours are also reported.
Disease EpidemiologyThese are very rare tumours, accounting for only 0.03% of all carcinomas. They are more common in women than in men and mostly develop after childbirth. It usually develops in people between the ages of 10 and 40.
Disease Etiology (Cause)There is no well-known reason. However, certain risk factors such as familial polyposis, a history of trauma, and hormonal imbalances are thought to be responsible for the development of desmoid tumours.
Signs and Symptoms
- A mass or lump at the tumour site
- Pain at the tumour site
- Large abdominal tumours can cause intestinal obstruction and constipation.
- Large tumours in an arm, leg, or joint can cause limitation of movement, such as difficult walking
- Imaging techniques like X-ray, USG (ultrasonography), MRI, CT-Scan, and PET –scan to detect the size and extent of the tumour.
- Tumour biopsy and histopathological examination
- Colonoscopy and Fundal examination to rule out familial adenomatous polyposis disease