What is Dermatofibrosarcoma Protuberans?Dermatofibrosarcoma Protuberance is a rare soft tissue cancer that arises from the deep layers of the skin. It is an aggressive tumor that can invade surrounding tissue but rarely spreads to other parts of the body. It also tends to recur after treatment. The most common sites for dermatofibrosarcoma are the chest and abdomen, but it can also develop in the arms, legs, head, and neck.
Disease Etiology (Causes)There is no well-known cause. However, certain chromosomal aberrations (changes in chromosomal structure and numbers), trauma or injury, surgical burns, scars, and sites of vaccinations are the risk factors for the development of dermatofibrosarcoma protuberance.
Disease EpidemiologyIt accounts for approximately 1% of all soft tissue cancers. The annual incidence is 3 cases per million populations. It is equally common among both the male and female populations. The average age of the disease development is 20-50 years.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- A slowly growing tumor that appears as a papule (small pimple or swelling on the skin) or a patch that can grow to a lump or mass.
- In advanced cases, it may bleed or ulcerate
DiagnosisThe following diagnostic techniques and procedures can be used to make a diagnosis these are
- Diagnostic imaging techniques such as USG, CT-scan, MRI, and PET scan can be used to detect the site, size, and extent of the tumor.
- Skin biopsy