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Clear Cell Adenocarcinoma of the Vagina – Symptoms, Treatment & Support

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Posted by adeel | Apr 24, 2023

What is Clear Cell Adenocarcinoma of the Vagina?

Clear cell adenocarcinoma of the vagina is an exceedingly rare subtype of vaginal adenocarcinoma, a cancer that originates in the glandular cells of the vaginal tissue. The term “clear cell” refers to the appearance of the cancer cells when viewed under a microscope—they contain clear, glycogen-rich cytoplasm. This type of cancer has been associated with in-utero exposure to diethylstilbestrol (DES), a synthetic form of the hormone estrogen, although it can also occur in women who have not been exposed to DES.

Disease Aetiology (Causes)

The exact cause of clear cell adenocarcinoma of the vagina is not known, but it’s linked to exposure to diethylstilbestrol (DES) in the womb.

Diagnosis

The diagnosis of clear cell adenocarcinoma often involves:
  • Detailed medical history and physical examination
  • Biopsy of suspicious tissues
  • Imaging tests such as ultrasound, CT scan, or MRI to identify the size, location, and spread of the tumour

Treatment

The treatment for clear cell adenocarcinoma of the vagina typically involves a combination of strategies:
  • Surgery: The primary treatment, involves surgical removal of the tumour. Depending on the stage and extent of the disease, removal of additional structures may be necessary.
  • Radiation Therapy: This can be used before surgery to shrink the tumour, or after surgery to kill any remaining cancer cells.
  • Chemotherapy: Can be used in combination with surgery and radiation therapy, especially in more advanced cases or if the cancer recurs.

What Support can we Give for Clear Cell Adenocarcinoma of the Vagina?

Clear Cell Adenocarcinoma of the Vagina is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Clear Cell Adenocarcinoma of the Vagina, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

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Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
Donations — Without a Ribbon are grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
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Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.

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