What is a Carcinoid Tumour (Lung)?
Carcinoid Tumour (Lung) is a type of neuroendocrine tumour that arises from neuroendocrine cells found in the lungs. These tumours are relatively rare, accounting for about 1-2% of all lung cancers. Carcinoid tumours are usually slow-growing compared to other lung cancers, but they can produce hormone-like substances leading to characteristic symptoms. They can be classified into two main types: typical (which are less aggressive) and atypical (which have a slightly higher potential for metastasis).Symptoms
The symptoms of a lung carcinoid tumour might not always be specific and can mirror those of other respiratory conditions. Common symptoms include:- Cough, which might be chronic
- Hemoptysis (coughing up blood)
- Wheezing or shortness of breath
- Chest pain or discomfort
- In cases where the tumour produces hormones, symptoms can include flushing, diarrhea, rapid heartbeat, or weight gain.
Disease Aetiology (Causes)
The exact cause of lung carcinoid tumours is not clearly understood. However, some general risk factors for lung cancers can be associated with it:- Smoking: Though the direct link is weaker compared to other types of lung cancers.
- Family history of neuroendocrine tumours.
- Prior history of lung diseases like tuberculosis.
Diagnosis
For a conclusive diagnosis of a lung carcinoid tumour, the following diagnostic tools and methods are often utilised:- Imaging studies: Chest X-ray or CT scans can help identify the tumour.
- Bronchoscopy: Allows for a visual examination of the airways and potential biopsy.
- Biopsy: A tissue sample is taken and analysed under a microscope to confirm the presence of carcinoid cells.
- Octreotide scan: This can be used to locate tumours by injecting a radioactive hormone into the bloodstream, which is then taken up by carcinoid cells.
Treatment
The best treatment approach largely depends on the size, location, and classification (typical or atypical) of the tumour:- Surgery: The primary treatment for localized tumours. Depending on the tumour’s location, this might include wedge resection, lobectomy, or pneumonectomy.
- Somatostatin analogues: Drugs like octreotide or lanreotide can help manage symptoms in hormone-producing tumours.
- Targeted therapies: Newer drugs that specifically target characteristics of carcinoid cells.
- Radiation therapy: Especially if the tumour cannot be completely removed or for pain relief in metastatic cases.
- Chemotherapy: Less commonly used, but can be effective, especially for atypical carcinoids.