What is Biphasic Synovial Sarcoma?Biphasic synovial sarcoma is a rare, high-grade soft tissue sarcoma that usually develops in adults at a younger age. Although biphasic synovial sarcoma can develop anywhere in the body, it develops in the arms and legs in 68.7% of cases, and its less common sites are the chest, head, neck, and abdomen. Among the limbs, the knee is the most commonplace of its development.
What is a Sarcoma?This is a type of cancer that arises from transformed connective tissue cells. Connective tissues are the types of tissues that form bones, cartilage, fat, vascular, and lymphatic tissues.
Disease EpidemiologyThe incidence of synovial sarcoma is 7% of all soft tissue sarcomas. It is slightly predominant in females as compared to males. Biphasic synovial sarcoma most often develops in adolescents and young people with a peak incidence of 36 years.
Disease EtiologyA certain chromosomal translocation (part of a chromosome is passed on to other chromosomes) is the cause of biphasic synovial sarcoma.
Signs and SymptomsCommon symptoms of biphasic synovial sarcoma are:
- Pain at the cancer site
- Lump or mass at the cancer site
- In rare cases, it can also affect the underlying bone