What is B-cell Prolymphocytic Leukemia?
B-cell prolymphocytic leukemia is cancer (rapid, uncontrolled division) of immature B- and T-lymphocytes (white blood cells) in the blood, bone marrow, and spleen. It is an aggressive tumor and has a poor prognosis. Mature B and T lymphocytes are white blood cells that help to fight various diseases caused by microorganisms. With prolymphocytic leukemia of B cells, due to a deficiency of mature B and T lymphocytes, the immune system has a low ability to fight various infections.
B-cell lymphocytic leukemia accounts for approximately less than 1% of all leukocyte cancers. The average age at the development of the disease is 65-70 years. It is more prevalent in men than in women. It is more common in white people.
There is no well-known cause, but certain genetic mutations and exposure to radiation and harmful chemicals are responsible for the development of B-cell prolymphocytic leukemia.
Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are
- Night sweats
- Weight loss
- Enlargement of the spleen than normal size
- Higher white blood cell count on Complete blood count examination (CBC)
- Lower red blood cell count on complete blood count examination (CBC)
- Chronic and recurrent infections
- The lower number of a platelet on complete blood count examination (CBC)
- Bleeding and bruising due to lower platelet count
The following diagnostic techniques and procedures can be used to make a diagnosis these are
- Complete blood count (CBC)
- Diagnostic imaging techniques such as USG, CT-scan, MRI, and PET scan can be used to detect the site, size, and extent of the tumor.
- Bone marrow biopsy
It is a rare disease that is currently incurable; there are treatment options available to reduce the severity of the disease and to increase the life expectancy of patients. Surgical resection of the tumor (surgical removal of the tumor) and spleen, chemotherapy, radiation therapy, and stem cell transplantation are the main treatment options.
What Support can we Give for Follicular Dendritic Cell Sarcoma?
B-cell Prolymphocytic Leukemia is a rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as B-cell Prolymphocytic Leukemia we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways: