What is Angiosarcoma?Angiosarcoma is a type of blood cancer that arises from the cells lining the blood and lymph vessels in the body. It can develop anywhere in the body, but most commonly affects the skin, breasts, spleen, and other deep tissues of the body. Angiosarcoma, if it develops under the skin, is called cutaneous angiosarcoma and is the most common type of angiosarcoma among all types of angiosarcoma. Cutaneous angiosarcoma most often develops on the skin of the skull (scalp) and face. It accounts for approximately 25% of deep tissue angiosarcomas and approximately 8% of breast tissue angiosarcomas.
Disease CausesThere is no well-known cause, however, there is an association between lymphedema (it is a condition in which fluid accumulates in the tissues due to blockage of the lymphatic vessel and cause swelling) and the development of angiosarcoma The exposure to certain types of radiation or radiation therapy and certain chemicals such as vinyl chloride, arsenic, and thorium chloride, are risk factors for angiosarcoma.
Signs and SymptomsSigns and symptoms of angiosarcoma depend upon the type and site of origin of cancer.
- Bruise like purple-coloured raised area of the skin
- This purple-coloured lesion can grow with time
- Swelling around the lesion
- Bleeding from the lesion on scratching
- Angiosarcoma of the liver or heart can often cause pain
- It can also develop as a soft palpable mass or lump
DiagnosisThe following diagnostic techniques and procedures can be used to make a diagnosis these are
- Diagnostic imaging techniques such as USG, CT-scan, MRI, and PET scan can be used to detect the site, size, and extent of the tumour.
- Tumour biopsy and histopathology