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Adenosquamous Carcinoma of the Vagina – Symptoms, Treatment & Support

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Posted by Matthew O’Connor | Apr 24, 2023

What is Adenosquamous Carcinoma of the Vagina?

Adenosquamous carcinoma of the vagina is an extremely rare type of cancer that contains two types of cells: glandular (adenocarcinoma) and squamous cells. It combines features of the two most common types of vaginal cancer, squamous cell carcinoma and adenocarcinoma. The disease is usually aggressive, often presenting at an advanced stage. Due to its rarity, there is limited knowledge about its exact aetiology, ideal treatment methods, and long-term prognosis.

Disease Aetiology (Causes)

The exact cause of adenosquamous carcinoma of the vagina is unknown. Like most cancers, it likely occurs when there’s a mutation in the DNA of cells, causing them to grow and divide in an uncontrolled way, forming a tumour. Risk factors may be similar to those of squamous cell carcinoma and adenocarcinoma of the vagina, which includes age, smoking, human papillomavirus (HPV) infection, and in-utero exposure to diethylstilbestrol (DES).

Diagnosis

Adenosquamous carcinoma is often diagnosed through:
  • Detailed medical history and physical examination
  • Biopsy of suspicious tissues
  • Imaging tests such as ultrasound, CT scan, or MRI to determine the size and location of the tumour and to check if the cancer has spread to other parts of the body

Treatment

The treatment for adenosquamous carcinoma of the vagina often involves a combination of strategies: Surgery: Surgical removal of the tumour is usually the first line of treatment. Depending on the stage of the disease, it might be necessary to remove surrounding structures as well. Radiation Therapy: Can be used pre-surgery to shrink the tumour, or post-surgery to kill any remaining cancer cells. Chemotherapy: Can be used in combination with surgery and radiation therapy, especially in advanced cases or if the cancer recurs.

What Support can we Give for Adenosquamous Carcinoma of the Vagina?

Adenosquamous Carcinoma of the Vagina is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Adenosquamous Carcinoma of the Vagina, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

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Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
Donations — Without a Ribbon are grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
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Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.

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