What is Adenocarcinoma of the Esophagus or Esophageal adenocarcinoma?
Adenocarcinoma of the esophagus also known as Esophageal adenocarcinoma is a type of cancer that forms in the glandular cells of the esophagus, the tube that carries food from the throat to the stomach. It is one of the two main types of esophageal cancer, with the other being squamous cell carcinoma. Adenocarcinoma is more commonly found in the lower part of the esophagus and is often associated with a condition called Barrett’s esophagus, where chronic acid reflux leads to changes in the esophageal lining.
Symptoms
Symptoms of esophageal adenocarcinoma may include:
- Difficulty swallowing (dysphagia), initially with solid foods and then with liquids as the tumour grows.
- Unintentional weight loss.
- Chest pain or discomfort.
- Chronic cough or hoarseness.
- Indigestion or heartburn.
- Vomiting or regurgitation of food.
Disease Aetiology (Causes)
The exact cause of adenocarcinoma of the esophagus is not fully understood, but several risk factors have been identified:
- Chronic gastroesophageal reflux disease (GERD) and Barrett’s esophagus.
- Obesity, particularly fat accumulation around the abdomen.
- Smoking and excessive alcohol consumption.
- A diet low in fruits and vegetables.
- Being male and over the age of 50.
Diagnosis
Diagnosing adenocarcinoma of the esophagus typically involves:
- Endoscopy: A procedure using a flexible tube with a camera to examine the esophagus and take tissue samples (biopsy).
- Imaging Tests: Including barium swallow X-rays, CT scans, MRI, and PET scans to assess the extent of the cancer.
- Biopsy: Microscopic examination of the tissue sample to confirm the diagnosis.
Treatment
Treatment for esophageal adenocarcinoma depends on the stage of the cancer and may include:
- Surgery: To remove the tumour and some surrounding tissue, possibly including part of the esophagus and nearby lymph nodes.
- Chemotherapy: Often used before surgery (neoadjuvant) to shrink the tumour or after surgery (adjuvant) to kill any remaining cancer cells.
- Radiation Therapy: Usually combined with chemotherapy, either before or after surgery.
- Targeted Therapy: For tumours with specific genetic changes.
- Immunotherapy: Used in certain cases, especially for advanced or metastatic cancer.
What support can we give for Adenocarcinoma of the Esophagus?
Adenocarcinoma of the Esophagus is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Adenocarcinoma of the Esophagus, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways: