What is Acral Lentiginous Melanoma of the Skin?
Acral lentiginous melanoma of the skin is a rare type of skin cancer that arises from melanin (the pigment that gives color to the skin and eyes) producing cells of the skin of palms and soles or under the nails. When this type of melanoma develops on the extremities, it is referred to as acral which means extremity in Greek. The chances of developing acral lentiginous melanoma of the skin are high in weight-bearing areas of the foot skin such as the heel, forefoot, and lateral side of the foot. Acral lentiginous melanoma of the skin is usually diagnosed at a later stage than other types of skin cancer.Disease Causes
There is no known cause; however, some genetic and inherited mutations can form malignant pigment cells along the epidermis’s basal layer. It is a less common type of melanoma and accounts for only 2-3% of all types of skin cancer. The mean age for developing acral lentiginous melanoma of the skin is 62 years. The risk of the development of this carcinoma of the skin increases with age. It is equally common in both males and females.Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are- Unexplained lines or marks on nails
- Black, gray r brown colored tan o the skin with irregular margins
- A thick patch of skin on the sole or palm
- Itching on the affected skin
- Redness on the affected skin
- Changes in any skin growth or changes in the mole
Diagnosis
- Narrow margin excisional biopsy
- Histopathology